rs964184, ZPR1

N. diseases: 47
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASCAT Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits. 28548082 2017
VLDL cholesterol measurement
CUI: C0523560
Disease: VLDL cholesterol measurement
0.700 GeneticVariation GWASCAT Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits. 28548082 2017
Dyslipidemias
CUI: C0242339
Disease: Dyslipidemias
0.020 GeneticVariation BEFREE We also demonstrate that rs964184 has a large effect (odds ratio, 1.74) and is more frequent in the Mexican population, and thus it may contribute to the high predisposition to dyslipidemias in Mexicans. 20160193 2010
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASCAT Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. 31560688 2019
Dyslipidemias
CUI: C0242339
Disease: Dyslipidemias
0.020 GeneticVariation BEFREE There were significant associations between rs1260333 (OR is 0.82, 95 % CI 0.74-0.92, p ~ 3.96 × 10(-4)), rs1260326 (OR is 0.82, 95 % CI 0.74-0.92, p ~ 5.31 × 10(-4)), and rs964184 (OR is 1.36, 95 % CI 1.20-1.55, p ~ 1.89 × 10(-6)) and dyslipidemia. 23832694 2013
Hypochondroplasia (disorder)
CUI: C0410529
Disease: Hypochondroplasia (disorder)
0.010 GeneticVariation BEFREE The ZNF259 rs2075290, ZNF259 rs964184</span> and BUD13 rs10790162 SNPs were significantly associated with serum lipid levels in both HCH and non-HCH populations (P < 0.008-0.001). 24780069 2014
High density lipoprotein measurement
0.800 GeneticVariation GWASCAT The impact of low-frequency and rare variants on lipid levels. 25961943 2015
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASCAT The impact of low-frequency and rare variants on lipid levels. 25961943 2015
Low density lipoprotein cholesterol measurement
0.800 GeneticVariation GWASCAT The impact of low-frequency and rare variants on lipid levels. 25961943 2015
Serum total cholesterol measurement
CUI: C1445957
Disease: Serum total cholesterol measurement
0.800 GeneticVariation GWASCAT The impact of low-frequency and rare variants on lipid levels. 25961943 2015
Anemia, Sickle Cell
CUI: C0002895
Disease: Anemia, Sickle Cell
0.010 GeneticVariation BEFREE The G-risk allele rs964184/ZPRI ZNF259/ZPR1 gene (GC + GG genotypes) was associated with increased levels of TG in children ≥10 years old (p = 0.045) and the atherogenic ratio TG/HDL-C (p = 0.032) in SCD. 31670185 2020
Hypertriglyceridemia
CUI: C0020557
Disease: Hypertriglyceridemia
0.830 GeneticVariation BEFREE The G-G-A-A-C-C haplotype, carrying rs964184-G-allele, was associated with increased risk of HCH (OR: 1.35, 95% CI: 1.10, 1.66, P = 0.005) and HTG (OR: 1.75, 95% CI: 1.39, 2.21, P = 0.000). 24780069 2014
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.010 GeneticVariation BEFREE The association between rs964184 and prostate cancer risk was stronger among homozygous carriers of the minor allele (OR = 0.27; 95% CI: 0.09, 0.83). 24623848 2014
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.010 GeneticVariation BEFREE The association between rs964184 and prostate cancer risk was stronger among homozygous carriers of the minor allele (OR = 0.27; 95% CI: 0.09, 0.83). 24623848 2014
Reticulocyte count (procedure)
CUI: C0206161
Disease: Reticulocyte count (procedure)
0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
Platelet Component Distribution Width Measurement
0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
RDW - Red blood cell distribution width result
0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
Corpuscular Hemoglobin Concentration Mean
0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
Red cell distribution width determination
0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
Platelet mean volume determination (procedure)
0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
Cardiovascular Diseases
CUI: C0007222
Disease: Cardiovascular Diseases
0.710 GeneticVariation BEFREE The 11q23.3 genomic region-rs964184-is associated with cardiovascular disease in patients with rheumatoid arthritis. 24131021 2013
Hypertriglyceridemia
CUI: C0020557
Disease: Hypertriglyceridemia
0.830 GeneticVariation BEFREE Sixteen SNPs were significantly associated with an increased risk of HTG development, with odds ratios (ORs) (95% confidence interval [CI]) varying from 1.40 (1.01-1.95) to 4.69 (3.29-6.68) (rs964184 within the APOA5 gene). 31222479 2019
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.830 GeneticVariation GWASCAT Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. 24262325 2014
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.830 GeneticVariation BEFREE Recently, the rs964184 polymorphism has been associated with coronary artery disease in nonrheumatic Caucasian individuals. 24131021 2013
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.730 GeneticVariation BEFREE Recently, the rs964184 polymorphism has been associated with coronary artery disease in nonrheumatic Caucasian individuals. 24131021 2013